Journal: Frontiers in Neuroscience
Article Title: Alterations in learning-related cortical activation and functional connectivity by high-definition transcranial direct current stimulation after stroke: an fNIRS study
doi: 10.3389/fnins.2023.1189420
Figure Lengend Snippet: Study design. (A) Experimental paradigm. (B) Application of HD-tDCS. When a participant’s lesion was on the right side, the anode was placed on C4, and the cathodes were placed on C2, C6, FC4, and CP3. When a participant’s lesion was on the left side, the anode was placed on C3, and the cathodes were placed on C1, C5, FC3, and CP5. In the real HD-tDCS condition, a constant current was delivered at 1 mA for 20 min, with ramp-up and-down phases of 30 s. In the sham HD-tDCS condition, current was ramped up from 0 to 1 mA during the first 30 s, then ramp-down to 0 mA during the next 30 s, and remain at 0 mA for the next 20 min. (C) fNIRS measurement during the SFTT and the fNIRS topomap. A star appeared on the black screen for 600 ms, and then an empty black screen appeared for 400 ms after the star disappeared. HD-tDCS, high-definition transcranial direct current stimulation; fNIRS, functional near-infrared spectroscopy; SFTT, sequential finger tapping task; Nz, nasion; Iz, inion; LPA, left pre-auricular; RPA, right pre-auricular.
Article Snippet: The cortical activation map produced during the SFTT with the affected hand was analyzed using statistical parametric mapping (SPM) analysis with the Near-Infrared Spectroscopy-Statistical Parametric Mapping open-source software package (NIRS-SPM) ( ) implemented in MATLAB ® (MathWorks, Inc., Natick, MA, United States).
Techniques: Functional Assay, Spectroscopy